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Key Players And Innovative Start-Ups In Nutraceuticals: Emerging Strategies In Ingredients, Pharma, Food And Drinks-Aarkstore Enterprise

Pharmaceuticals, on the other hand, are bioactive compounds intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease. Pharmaceuticals are most often new chemical entities.

Well known nutraceuticals include essential fatty acids such as omega-3 oils, probiotics, prebiotics, plant sterols, botanicals, superfruit extracts, carotenoid antioxidants and soy protein/isoflavones. Over the past few years, most of these nutraceutical ingredients have made good progress in the marketplace and are now available in a wide range of foods and drinks, as well as supplements. Some have also been developed as pharmaceuticals.

The consumer environment is driving growth in the nutraceuticals market. Over the past decade, consumers have become more concerned for their health and are increasingly inclined to self-medicate. Healthcare providers, too, are keen to shift some of the burden of healthcare costs to individuals and recognize that functional foods may provide alternatives to medications. These factors are reflected in the current market for ingredients in the health and nutrition sector, which was estimated to be worth US$4 billion in 2009.

Key features of this report

• Identify leading companies at the forefront of the nutraceuticals industry who will drive the market for a new generation of "value added" health products.

• Provide case studies of these leading companies in the finished goods (foods and drinks), ingredients and other raw materials, or pharmaceutical sectors.

• Analyze the key trends and issues confronting the different industry sectors at this time.

• Review the backgrounds, discovery strategies and business models of new and innovative entrants to this marketplace.

Scope of this report

• Identify the companies leading the field in the nutraceuticals industry from across a range of different market sectors

• Review their key products and the ways in which these products are being marketed to consumers

• Learn more about the increased efforts of these companies to establish the health benefits of their products in clinical trials

• Identify innovative companies and discover the potential of their various approaches for discovery and marketing novel nutraceuticals

Key Market Issues

• The food market is changing: Over the past decade, consumers have become more concerned for their health and are increasingly inclined to self-medicate. Healthcare providers, too, are keen to shift some of the burden of healthcare costs to individuals and recognize that functional foods may provide alternatives to medications. These factors are reflected in the current market for ingredients in the health and nutrition sector, which was estimated to be worth US$4billion in 2009.
• Nutraceuticals and pharmaceuticals are related in that both are types of compound that demonstrate bioactive properties. Nutraceuticals are substances that are extracted from foods and are used either to fortify other food products in order to enhance their nutritional properties or are taken as dietary supplements in the form of pills, capsules of soft-gels. The clinical evidence behind a nutraceutical products varies widely; some have been tested with pharmaceutical rigor to demonstrate properties beneficial to health, while for other the evidence to support such claims is slim.

Key findings from this report

• New food and drink regulations were introduced in Europe in 2006 and have been generating uncertainty and frustration throughout the industry. The European Food Safety Authority is processing more than 4,000 generic health claims, as well as health claims for emerging and proprietary science or disease risk reduction. The regulator has rejected a large number of the applications reviewed to date (September 2009) and has missed a number of deadlines, suggesting that the overall process may take much longer than expected.

• FDA regulations are generally regarded as less stringent than those in the EU. Nevertheless, they come under criticism for not allowing companies to use in their product labeling relevant data generated in a clinical setting that links the food with a health benefit. Some of the smaller, innovative companies reviewed for this report are developing their business models with this fact in mind.

Key questions answered

• Which companies are the market leaders in the nutraceuticals industry, as identified from a review of finished goods companies, raw materials manufacturers and pharmaceutical companies?

• What are the key products of these companies and how do they exemplify the future direction of the nutraceutical industry?

• How are the market leaders approaching the need for research to back their products with health claims that are understandable by the consumer?
 
 
  Table of Contents : 
Table of Contents
Key Players and Innovative Start-ups in Nutraceuticals: Emerging strategies in ingredients, pharma, food and drinks
Executive summary 10
Defining nutraceuticals 10
Market leaders: food and drinks manufacturers 11
Market leaders: ingredients 12
Market leaders: pharmaceutical companies 13
Developing new ingredients: innovative start-up companies 14
Market drivers and trends 15
Chapter 1 Defining nutraceuticals 18
Summary 18
Introduction 19
Defining nutraceuticals 20
Examples of nutraceuticals 22
Omega-3 oils 24
Probiotics 25
Prebiotics 28
Plant stanols and sterols 29
Superfruits and antioxidants 30
The nutraceuticals market 31
Report outline 34
Chapter 2 Market leaders: Food and drinks companies 38
Summary 38
Introduction 39
Market Leaders: Case studies 40
Case study: Nestlé 40
Case study: Unilever 46
Case study: Groupe Danone 50
Case study: PepsiCo 54
Case study: Coca-Cola 56
Conclusions 58
Chapter 3 Market leaders: Ingredients 62
Summary 62
Introduction 63
Companies with diverse nutraceutical portfolios 64
Case study: DSM Nutritionals 64
Case study: Cognis 68
Case study: Cargill Inc 70
Case study: Ajinomoto 72
Case study: Kerry Group 74
Case study: Glanbia Foods 76
Probiotics 79
Case study: Chr. Hansen 79
Case study: Danisco 82
Prebiotics 85
Case study: BENEO 85
Fats and oils 87
Case study: Ocean Nutrition Canada 88
Agriculture 91
Case study: Dow AgroSciences 92
Case study: Monsanto 93
Case study: DuPont 93
Conclusions 94
Chapter 4 Market Leaders: Pharmaceutical companies 96
Summary 96
Introduction 97
Market leaders: Case studies 99
Case Study: Abbott Nutrition 99
Case study: Bayer Consumer Care 101
Case study: Pfizer 103
Case study: GSK Consumer Healthcare 105
Case study: McNeil Nutritionals 107
Case study: Mead Johnson Nutritionals 108
Discussion 109
Chapter 5 Developing new ingredients: Innovative start-up companies 112
Summary 112
Introduction 113
Case study: Advana Science 115
Case study: WellGen Inc 116
Case study: InterMed Discovery 118
Case study: Provexis 119
Case study: Clasado Ltd 122
Case study: Cambridge Theranostics Ltd 123
Case Study: HerbalScience Group 125
Business models 126
Conclusions 130
Chapter 6 Market drivers and trends 132
Summary 132
Introduction 133
Regulatory considerations 133
Japan 134
United States 135
Europe 137
Intellectual property 140
Development costs 141
Opportunities in the nutraceuticals market 142
Opportunities for medical foods 144
International emerging markets 146
The science driving the future foods market 148
Nutrigenomics and nutrigenetics 148
Epigenetics 148
Nanotechnology 149
Conclusions 149
Chapter 7 Appendix 152
Primary research methodology 152
Acknowledgments 152
Glossary 153
Index 156
Bibliography 158
Endnotes 163

List of Figures
Figure 1.1: Different types of medical food and their uses 22
Figure 1.2: The health and nutrition sector 32
Figure 1.3: Key US consumer health concerns, 2009 33
Figure 1.4: The role of food and pharmaceuticals in the healthcare continuum 34
Figure 1.5: End products for nutraceutical ingredients 35
Figure 2.1: Danone's sales figures by business line and sales region (2008) 50
Figure 3.1: Technologies for nutraceutical product development at Kerry Group 75
Figure 3.2: Defining Danisco's Bioactives and Enabler ingredients 82
Figure 5.1: InterMed Discovery's active ingredient pipeline 118
Figure 5.2: A comparison of research paradigms in the pharmaceutical and nutraceutical industries 127
Figure 5.3: Examples of business models adopted by innovative nutraceutical companies 128
Figure 6.1: Opportunities and threats for the nutraceuticals industry 133
Figure 6.2: Types of EFSA health claims 138
Figure 6.3: Key attributes for product success 143
Figure 6.4: Opportunities for medical foods 145
Figure 6.5: Growth in the number of potential consumers from developing and emerging countries: 2008-2018 147

List of Tables
Table 1.1: Examples of nutraceuticals 23
Table 1.2: Omega-3 and Omega-6 fatty acids and their dietary sources 24
Table 1.3: Examples of common antioxidants present in food 30
Table 2.1: Leading food companies: revenues and product focus 39
Table 2.2: Nestlé sales by product area (CHFm), 2008 40
Table 2.3: Nestlé's Branded Active Benefits 42
Table 2.4: Examples of brands from Nestlé Nutrition 43
Table 2.5: Functional ingredients included in Danone's dairy products 51
Table 3.6: Market leaders: Ingredients 63
Table 3.7: Nutraceutical or personalized nutrition companies participated in by DSM Venturing 67
Table 3.8: Examples of ingredients from Danisco 83
Table 4.1: Market Leaders: Pharma 98
Table 4.2: Leading nutraceutical products from Abbott Nutrition 100
Table 4.3: Leading nutraceutical products from Bayer Consumer Care 102
Table 4.4: Leading nutritional products from Pfizer 104
Table 5.1: Innovative companies and start-ups in the nutraceutical sector 114
Table 5.2: Examples of innovative companies exploring novel manufacturing methods 115
Table 5.3: Products or projects in development at Provexis 120
Table 6.1: Health claims meeting significant scientific agreement 137
 
 

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